No one can know for sure whether a disease could develop some sort of resistance to nanosilver in the future, but to my knowledge, it hasn’t happened yet.
Catalytic / mechanical vs Chemical / biochemical
What is the explanation? As a layman, I don’t really understand it. But the explanation given to me is that when the nanosilver particle wraps itself around a pathogen and kills it, the process is not a chemical or biochemical one, but rather, a catalytic process, more akin to something mechanical, where the silver “flake’ wraps itself around the pathogen and kills it somehow.
The nanosilver then remains as it was, silver with a positive charge, even after it has killed the pathogen.
This would imply that the pathogen never gets a chance to change its chemical structure in some way that makes it resistant to the nanosilver. Someone with scientific knowledge would be able to explain it better, but the important thing is, if no disease can develop a resistance to the nanosilver, that is really good news!